منابع مشابه
MicroRNA and cancer chemoprevention.
MicroRNAs (miRNA) are a group of naturally occurring, small, noncoding, and single-strand RNA molecules that regulate gene expression at the posttranscriptional and translational levels. By controlling the expression of oncogenic and tumor suppressor proteins, miRNAs are believed to play an important role in pathologic processes associated with malignant progression including tumor cell prolife...
متن کاملMicroRNA: A New Player for Cancer Chemoprevention.
In 2012, a total of 1,638,910 new cases and 577,190 deaths from cancer are projected to occur in the United States [1]. From 2004 to 2008, the overall cancer death rate was decreased by 1.8% in men versus 1.6% in women yearly, which may result from the successful implementation of early detection, treatment, and prevention methods [1]. Although its potential has not yet been fully realized, che...
متن کاملEvaluation of MicroRNA-99a and MicroRNA-205 Expression Levels in Bladder Cancer
Bladder cancer is the second most common cancer in the genitourinary tract, showing often recurrence and progresse into invasive states. Epigenetic changes, such as microRNA alteration are involved in bladder cancer tumorigenesis through a variety of signaling pathways. The epigenetic state depends on geographic and lifestyle conditions. The aim of this study was to investigate the expression l...
متن کاملQuercetin and Cancer Chemoprevention
Several molecules present in the diet, including flavonoids, can inhibit the growth of cancer cells with an ability to act as "chemopreventers". Their cancer-preventive effects have been attributed to various mechanisms, including the induction of cell-cycle arrest and/or apoptosis as well as the antioxidant functions. The antioxidant activity of chemopreventers has recently received a great in...
متن کاملOral Cancer and Chemoprevention
Oral cancer is one of the major global threats to public health. The development of oral cancer is a tobacco-related multistep and multifocal process involving field cancerization and carcinogenesis. As, curative therapy available for oral cancer often results in debilitating changes in appearance, speech, swallowing and breathing, preventive strategies are desirable. Chemoprevention , is the u...
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ژورنال
عنوان ژورنال: Cancer Prevention Research
سال: 2013
ISSN: 1940-6207,1940-6215
DOI: 10.1158/1940-6207.capr-13-0032